Psychoactive Substances

Psychoactive substances are natural or synthetic substances that act on the central nervous system and alter mental processes such as mood, perception, cognition, consciousness, and behaviour. These substances may be legally prescribed medications (e.g., pain medications or sedatives), legally available substances such as alcohol or caffeine, or controlled or illicit drugs. Psychoactive substances can be used for medical, social, cultural, or recreational purposes, but some carry risks of misuse, dependence, and health or social harms when used in harmful ways. 

Drug Use in England and Wales

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Illegal drug use trends among 16- to 59-year-olds in England and Wales are examined in a new UK Home Office release based on the findings from the 2016 – 2017 Crime Survey for England and Wales (CSEW). The survey used a representative...

An Expanding World of Novel Psychoactive Substances: Opioids

Scientific article
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The abuse of novel psychoactive substances (NPS) has been increasing dramatically worldwide since late 2000s. By the end of 2015, more than 560 NPS had been reported to the European Monitoring Centre for Drugs and Drug Addiction. Although...

Drug Misuse and Dependence: UK Guidelines on Clinical Management

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Often called the Orange Book, this is guidance for clinicians treating people with drug problems. This 2017 version offers new guidelines on: prison-based treatment new psychoactive substances and club drugs mental health co-morbidity...

An Approach to the New Psychoactive Drugs Phenomenon

Scientific article
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ABSTRACT Background: The new psychoactive drugs (NPD) are those that represent a danger to public health and are not prohibited by conventions on international narcotics. The concept also includes new contexts and new routes of consumption...

European Masters in Drug and Alcohol Studies

News
The European Masters in Drug and Alcohol Studies is designed to stimulate reflection and debate on crucial topics in substance use and misuse from a multi-disciplinary, European and cross-national perspective. It is run jointly by four...

High-Risk Drug Use and New Psychoactive Substances

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‘High-risk drug use and new psychoactive substances’, a new report from the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), takes a look at the emergence of more problematic forms of new psychoactive substance use among a...

Treatment for Opioid Use Disorder: What's There to Learn?

Scientific article
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This misuse of prescription opioids is a major public health challenge. Buprenorphine-naloxone (bup-nx) is typically used to treat opioid use disorders. However, the drug’s clinical trial primarily involved heroin users. It was therefore...