Psychoactive substances are natural or synthetic substances that act on the central nervous system and alter mental processes such as mood, perception, cognition, consciousness, and behaviour. These substances may be legally prescribed medications (e.g., pain medications or sedatives), legally available substances such as alcohol or caffeine, or controlled or illicit drugs. Psychoactive substances can be used for medical, social, cultural, or recreational purposes, but some carry risks of misuse, dependence, and health or social harms when used in harmful ways.
Psychoactive Substances
Drug policy and the public good
Drug use has a significant impact on health published by illness, disability, and social problems, and the decision makers are increasingly interested in the development of evidence-based drug policy. Is fundamentanl to strengthen ties...
Substance Use among a Sample of Healthcare Workers in Kenya
ABSTRACT This study describes reported substance use among Kenyan healthcare workers (HCWs), as it has implications for HCWs’ health, productivity, and their ability and likelihood to intervene on substance use. The Alcohol Smoking and...
The Role of Adenosine Receptors in Psychostimulant Addiction
Adenosine receptors (AR) are a family of G-protein coupled receptors, comprised of four members, named A1, A2A, A2B, and A3 receptors, found widely distributed in almost all human body tissues and organs. To date, they are known to...
Effects of Prefrontal Transcranial Direct Current Stimulation and Motivation to Quit in Tobacco Smokers
Transcranial direct current stimulation (tDCS) applied over the dorsolateral prefrontal cortex (DLPFC) has been shown to reduce cravings in tobacco addiction; however, results have been somewhat mixed. In this study, we hypothesized that...
Detecting Novel and Emerging Drug Terms Using Natural Language Processing: A Social Media Corpus Study
ABSTRACT Background: With the rapid development of new psychoactive substances (NPS) and changes in the use of more traditional drugs, it is increasingly difficult for researchers and public health practitioners to keep up with emerging...
Misuse of Novel Synthetic Opioids: A Deadly New Trend
ABSTRACT Novel synthetic opioids (NSOs) include various analogs of fentanyl and newly emerging non-fentanyl compounds. Together with illicitly manufactured fentanyl (IMF), these drugs have caused a recent spike in overdose deaths, whereas...
The Diverse Reasons for Using Novel Psychoactive Substances
Abstract Background The increasing number of legally ambiguous and precarious Novel Psychoactive Substances (NPS) constitutes a challenge for policy makers and public health. Scientific and more in-depth knowledge about the motivations for...
Gender Differences in Substance Use and Psychiatric Distress among Medical Students
ABSTRACT Background: Medical student wellness has emerged as an important issue in medical education. The purpose of the present study was to obtain a comprehensive assessment of substance use, psychological distress, and help-seeking among...
Granulocyte-Colony Stimulating Factor Controls Neural and Behavioral Plasticity in Response to Cocaine
Cocaine addiction is characterized by dysfunction in reward-related brain circuits, leading to maladaptive motivation to seek and take the drug. There are currently no clinically available pharmacotherapies to treat cocaine addiction...
Psychological Distress, Family Functioning and Use of Psychoactive Substances in Administrative Workers of an Institution of Higher Education in Nicaragua
Alinka Patricia Avendaño Balladares Introduction: Professionals in the field of mental health and addictions try to identify situations that cause psychoactive substances use in the population, especially the working population, due to this...