Psychoactive substances are natural or synthetic substances that act on the central nervous system and alter mental processes such as mood, perception, cognition, consciousness, and behaviour. These substances may be legally prescribed medications (e.g., pain medications or sedatives), legally available substances such as alcohol or caffeine, or controlled or illicit drugs. Psychoactive substances can be used for medical, social, cultural, or recreational purposes, but some carry risks of misuse, dependence, and health or social harms when used in harmful ways.
Psychoactive Substances
Sociodemographic and family factors related to the use of psychoactive substances in adolescents
This article presents an analysis of the sociodemographic and family factors related to the use of psychoactive substances in adolescents in the tenth year of a public school in the Canton of Montes de Oca. The approach was quantitative...
Anomalies in global network connectivity associated with early recovery from alcohol dependence: A network transcranial magnetic stimulation and electroencephalography study
Abstract Although previous research in alcohol dependent populations identified alterations within local structures of the addiction ‘reward’ circuitry, there is limited research into global features of this network, especially in early...
Sulphated dehydroepiandrosterone serum levels are reduced in women with alcohol use disorder and correlate negatively with craving: A sex-separated cross-sectional and longitudinal study
Abstract Previous studies have established a role of sex hormones in alcohol use disorder (AUD).Only few clinical investigations with low numbers of patients with AUD have focused on the sulphated form of dehydroepiandrosterone (DHEA-S)...
From binge eating to binge drinking: A new and robust paradigm for assessing binge ethanol self-administration in male rats
Abstract Animal models of alcohol (ethanol) self-administration are crucial to dissect the neurobiological mechanisms underlying alcohol dependence, yet only a few of these induce pharmacologically relevant levels of alcohol consumption and...
Overcoming the pains of recovery: The management of negative recovery capital during addiction recovery pathways
Abstract: Pains experienced as a result of negative recovery capital are often thought to stimulate motivations for positive behavioural change, usually through a ‘rock bottom’ type moment. Whilst recovery capital and barriers to recovery...
Abuse Potential of Cathinones in Humans: A Systematic Review
Abstract Introduction and objective: Assessing the abuse potential of new substances with central nervous system activity is essential for preventing possible risks of misuse and addiction. The same methodology is recommended for the...
Culture of Care’ Barometer
An organisational culture is the collection of values, expectations, and practices that shape the overall feeling and actions among staff members. A culture of care is an environment that is created where people feel valued and supported as...
EMCDDA initial report on the new psychoactive substance 1-(3-chlorophenyl)-2-(methylamino)propan-1-one (3-chloromethcathinone, 3-CMC)
1-(3-Chlorophenyl)-2-(methylamino) propan-1-one (3-chloromethcathinone, 3-CMC) is a synthetic cathinone stimulant. It is a ring-substituted cathinone, which is structurally related to methcathinone and 4-chloromethcathinone (4-CMC). The...
UNODC supports 28 health care providers from all 14 regions in Senegal with a training on treatment and care of people who inject drugs in Senegal
Since December 2014, methadone maintenance treatment is available at the Centre de Prise en Charge Intégrée des Addictions à Dakar, Senegal (CEPIAD). This center, located within the Centre Hospitalier National Universitaire de Fann, allows...
DECCA Big Guides
Downloadable information on alcohol, drugs and tobacco.