Psychoactive substances are natural or synthetic substances that act on the central nervous system and alter mental processes such as mood, perception, cognition, consciousness, and behaviour. These substances may be legally prescribed medications (e.g., pain medications or sedatives), legally available substances such as alcohol or caffeine, or controlled or illicit drugs. Psychoactive substances can be used for medical, social, cultural, or recreational purposes, but some carry risks of misuse, dependence, and health or social harms when used in harmful ways.
Psychoactive Substances
Effect of screening, brief intervention and referral to treatment for unhealthy alcohol and other drug use in mental health treatment settings: a randomized controlled trial
Abstract Aims To test the efficacy of a brief intervention to reduce alcohol or drug use and to promote use of addiction services among patients seeking mental health treatment. Design and setting A multi-centre, longitudinal, two-group...
Quality Standards in Drug Use Disorder Treatment – Reading List
In this reading list, we provide resources to help engage our members with the latest knowledge, tools, and case studies on quality standards in substance use disorder treatment. These materials highlight international frameworks, research...
Is the Rise of Cannabis Induced Psychosis Unstoppable?
Attendance
online
Sept. 29th at 10:00 AM Eastern Time
The Global SMART Programme — A Strategic Response to the Synthetic Drug Problem, United Nations, New York
The global market for synthetic drugs has grown rapidly in recent years, with amphetamine-type stimulants (ATS) and new psychoactive substances (NPS) becoming a significant concern worldwide. ATS, which include amphetamine, methamphetamine...
Classification of Psychoactive Substances
This section from the UPC 2 Physiology and Pharmacology for Prevention Professionals (p130-133) introduces the main types of psychoactive substances, explains their effects on the brain and body, and clarifies that some commonly used legal...
UNODC (2014a), Global SMART Update
The rapid rise of synthetic drugs has become one of the world’s most pressing drug-related challenges. After cannabis, amphetamine-type stimulants (ATS) are the most widely used drugs globally, now surpassing cocaine and heroin. Alongside...
⚠️ Tusi ("Pink Cocaine"): What It Is, Risks and Where to Get Help
⚠️ Tusi ("Pink Cocaine"): What It Is, Risks and Where to Get Help
Global Launch – Universal Nurses Addiction Curriculum (UNAC)
On June 26, 2025, the International Consortium of Universities for Drug Demand Reduction (ICUDDR) marked an important milestone with the global launch of the Universal Nurses Addiction Curriculum (UNAC). This initiative, supported by the U...
ISSUP Nigeria Knowledge Update Series (29th Session): Beyond Tokenistic Roles: Harnessing The Power of Young People in Drug Use Prevention
ISSUP Nigeria presents the 29th session of its bi-monthly webinar in the Knowledge Update Series. This webinar will focus on the topic 'Beyond Tokenistic Roles: Harnessing The Power of Young People in Drug Use Prevention'.
World Drug Report 2025: Webinar on Key Trends and Policy Challenges for Africa
As a follow-up to our previous webinar outlining the Key Findings of the World Drug Report 2025, ISSUP on 28 August 2025 presented a review of the World Drug Report 2025 through an African lens. The webinar was moderated by Radolf Nortey...