Research from the University of Exeter has highlighted how childhood trauma can make individuals more sensitive to the pleasurable and motivational effects of opioids and less sensitive to the negative consequence of the drugs.

The research, which has been published in the journal of Addiction Biology, aimed to assess the impact of childhood trauma on responses to morphine and pain processing.

As part of a randomised control trial, 52 healthy people- 27 with a history of childhood abuse and neglect, and 25 who reported no such experiences in childhood- received either an active dose of...

Abstract

Background: Patients with opioid use disorder (OUD) often have complex health care needs. Methadone is one of the medications for opioid use disorder (MOUD) used in the management of OUDs. Highly restrictive methadone treatment—which requires patient compliance with many rules of care—often results in low retention, especially if there is inadequate support from healthcare providers (HCPs). Nevertheless, HCPs should strive to offer patient-centred care (PCC) as it is deemed the gold standard to care. Such an approach can encourage patients to be actively involved in their care...