The intersection of substance use with broader public health concerns.
Public Health
Repeated Exposure to the “Spice” Cannabinoid JWH-018 Induces Tolerance and Enhances Responsiveness to 5-HT1A Receptor Stimulation in Male Rats
Naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) is a synthetic compound found in psychoactive “spice” products that activates cannabinoid receptors. Preclinical evidence suggests that exposure to synthetic cannabinoids increases 5...
Adolescent Exposure to Toxic Volatile Organic Chemicals from E-Cigarettes
Abstract BACKGROUND: There is an urgent need to understand the safety of e-cigarettes with adolescents. We sought to identify the presence of chemical toxicants associated with e-cigarette use among adolescents. METHODS: Adolescent e...
Electronic Cigarette Use and Progression from Experimentation to Established Smoking
Abstract BACKGROUND: It has been shown that never-smoking adolescents who try electronic cigarettes (e-cigarettes) are at increased risk of subsequent conventional cigarette smoking. We evaluated associations between e-cigarette use and...
Proportion of Patients in South London with First-Episode Psychosis Attributable to Use of High Potency Cannabis
Summary Background The risk of individuals having adverse effects from drug use (eg. alcohol) generally depends on the frequency of use and potency of the drug used. We aimed to investigate how frequent use of skunk-like (high-potency)...
Medical Marijuana Laws and Adolescent Marijuana Use in the United States
Abstract Aims To conduct a systematic review and meta-analysis of studies in order to estimate the effect of US medical marijuana laws (MMLs) on past-month marijuana use prevalence among adolescents. Methods A total of 2999 papers from 17...
Risk of Violence-Related Injury from Alcohol Consumption and Its Burden to Society in Latin America and the Caribbean
Abstract Objective: To determine the relative risk (RR) and societal burden of injury related to alcohol-attributable intentional interpersonal violence (alcohol-attributable fraction or AAF), and the dose–response relationship, in Latin...
Cigarette Flavors, Package Shape, and Cigarette Brand Perceptions
Abstract Objective: In 2012, a new Brazilian regulation prohibited the use of flavor additives in tobacco products. To better understand the potential impact of this regulation, this study examines how flavor descriptors on cigarette...
Rural and Appalachian Disparities in Neonatal Abstinence Syndrome Incidence and Access to Opioid Abuse Treatment
Abstract Objective Incidence of neonatal abstinence syndrome (NAS) is increasing due to the rise in opioid use. Rural states like Kentucky have been disproportionally impacted by opioid abuse, and this study determines NAS burden nationally...
Contemporary Routes of Cannabis Consumption: A Primer for Clinicians
Abstract Although cannabis use is federally prohibited, medical cannabis is legal in some form in 30 states and the District of Columbia, and recreational use is legal in 8 states and the District of Columbia. The increasing legal...
2017 review INCB
International Narcotics Control Board report 2017
