The U.S. Drug Enforcement Administration (DEA) has released its 2025 National Drug Threat Assessment (NDTA), providing an overview of the threats posed by illicit drugs and the transnational criminal organizations involved in their production and trafficking. The report highlights the continuing impact of synthetic drugs, particularly fentanyl and methamphetamine, on public health, public safety, and national security.

While overdose deaths in the United States have declined significantly over the past year, synthetic drugs remain the leading driver of drug-related fatalities. The report also...

The UNODC Early Warning Advisory highlights a continued global expansion of new psychoactive substances (NPS), with nearly 1,400 substances reported worldwide. In 2024 alone, a record number of substances were identified, including over 100 newly detected compounds.

Synthetic opioids—particularly fentanyl analogues and nitazenes—are a growing concern, now reported across all regions. At the same time, benzodiazepine-type substances remain widely present in drug samples. A key emerging risk is polysubstance use , with a significant share of deaths involving multiple substances.

Overall, the...

This practical toolkit highlights the role of faith-based and community leaders in responding to the opioid crisis in the United States. Developed by the U.S. Department of Health and Human Services, it recognizes that community and faith organizations are often among the first to support individuals and families affected by addiction .

The toolkit encourages local action through prevention, recovery support, and community engagement, while emphasizing compassion, hope, and partnership. It also reflects growing recognition that addressing opioid use disorder requires collaboration between...

Opioid use during pregnancy and the postpartum period is increasing in the United States, yet many pregnant and parenting people face serious barriers to accessing effective treatment and supportive services. These barriers arise from fragmented systems such as healthcare, health insurance, child welfare, childcare, and the criminal justice system. This study uses in-depth interviews with healthcare providers, treatment leaders, local government officials, and pregnant and parenting people in a mid-Atlantic state to explore access to medication for opioid use disorder (MOUD), key treatment...

The ESPAD report presents the results of the eighth data-collection wave, which took place in 2024, and marks an impressive 30 years of data collection by this long-standing collaboration. More than 113 000 15- to 16-year-old students from 37 countries, including 25 EU Member States, took part. Since 1995, over 800 000 students have contributed, making ESPAD the most extensive harmonised data collection on substance use and risk behaviours in Europe, and the largest cross- national research project on adolescent substance use worldwide.

The Canadian Centre on Substance Use and Addiction (CCSA) transforms complex data into insights that reflect real human experiences. Every aspect of the Canadian Substance Use Cost and Harms (CSUCH) project represents individuals with lived or living experience of substance use, along with their families, workplaces, and communities.

A new resource highlights these journeys and the human cost of substance use through illustrated stories from people with lived experience and their families. The illustrations cover three key areas of the CSUCH project: healthcare, lost productivity, and...

The 2025 Annual Report to the Parliament on Drug Addictions in Italy offers a comprehensive overview of the current drug addiction landscape. Despite a slight decline in youth drug use for the first time since 2018, the report highlights ongoing challenges, particularly with substances like cocaine, synthetic opioids, and high-potency cannabis derivatives. Law enforcement and judicial efforts remain strong, and Italy continues to be a key collaborator in global anti-drug initiatives, particularly with countries in South America and the Indo-Pacific region.

The report also emphasizes the...

ISSUP, in collaboration with Faces & Voices of Recovery, has launched a new Global Recovery Network webinar series to spotlight diverse perspectives on recovery. The first webinar featured Dr. Haner Hernández, a respected expert in the field and a person in long-term recovery. Dr. Hernández currently serves as a Senior Consultant to the Massachusetts Department of Public Health and plays a key role in advancing health equity, workforce development, and recovery support. His presentation provided an insightful and inclusive overview of multiple pathways to recovery, grounded in both...