Factors Related to Simultaneous Cocaine and Alcohol Use for Clients in Treatment
Research shows that alcohol and cocaine are frequently used simultaneously.
cocaine
A Double Blind, Placebo Controlled Trial of Modafinil for the Treatment of Cocaine Dependence without Co-Morbid Alcohol Dependence
Like methadone for heroin dependence, modafinil is an oral medication with similar effects to cocaine but milder, slower in onset and longer-acting - properties which might help plug the gap in effective pharmacotherapies for dependence on...
Glucagon-Like Peptide-1 Receptor Activation in the Ventral Tegmental Area Attenuates Cocaine Seeking in Rats
Abstract Novel molecular targets are needed to develop new medications for the treatment of cocaine addiction. Here we investigated a role for glucagon-like peptide-1 (GLP-1) receptors in the reinstatement of cocaine-seeking behavior, an...
How Can Contingency Management Support Treatment for Substance Use Disorders? A Systematic Review
Rewarding people dependent on illegal drugs for not using those drugs is a controversial tactic, one this report from the European Union’s drug misuse centre found patchily effective in extending retention and reducing substance use as a...
Incubation of Cue-Induced Craving in Adults Addicted to Cocaine Measured by Electroencephalography
Key Points Question: Does cue-induced craving follow a parabolic trajectory as a function of duration of abstinence in humans with cocaine use disorders, as previously shown in preclinical studies? Findings: The results of this laboratory...
Transcranial Magnetic Stimulation of Medial Prefrontal and Cingulate Cortices Reduces Cocaine Self-Administration: A Pilot Study
Background: Previous studies have shown that repetitive transcranial magnetic stimulation (rTMS) to the dorsolateral prefrontal cortex may serve as a potential treatment for cocaine use disorder (CUD), which remains a public health problem...
Diagnosis of Stroke Due to Cocaine and Its Complications
Introduction: Cocaine is an independent cerebrovascular risk factor both for ischaemic and haemorrhagic events, above all among persons under 55 years of age. Report: A case report of stroke due to the consumption of cocaine is used to...
Dual Disorders in Individuals under Treatment for both Alcohol and Cocaine
Abstract Introduction: Descriptive data about co-occurrence of alcohol and cocaine consumption is scarce, despite its important prevalence. Dual disorders show high prevalence in clinical samples, and patients report worse evolution and...
The Role of Adenosine Receptors in Psychostimulant Addiction
Adenosine receptors (AR) are a family of G-protein coupled receptors, comprised of four members, named A1, A2A, A2B, and A3 receptors, found widely distributed in almost all human body tissues and organs. To date, they are known to...
Granulocyte-Colony Stimulating Factor Controls Neural and Behavioral Plasticity in Response to Cocaine
Cocaine addiction is characterized by dysfunction in reward-related brain circuits, leading to maladaptive motivation to seek and take the drug. There are currently no clinically available pharmacotherapies to treat cocaine addiction...