Major research breakthroughs over the past 30 years in the field of substance use prevention have served to:
(1) enhance understanding of pharmacological effects on the nervous systems and the health and social consequences of the use of psychoactive substances, particularly for children and adolescents;
(2) delineate the processes that increase vulnerability to or protect from initiation of substance use and progression to substance use disorders (SUDs) and, based on this understanding,
(3) develop effective strategies and practices to prevent the initiation and escalation of substance use...